As I was explaining to Heather, the original conception behind the Climatron was to provide what J. Baldwin would prototype using argon gas-filled pillows: a Garden of Eden dome.
These were later developed on a larger scale in Cornwall.
The homestead inside a dome, in some ways a cell nucleus, could have "flimsier" construction materials, though sometimes soundproofing is important.
A spiral staircase or elevator might connect the floors, but rain and wind would not be a factor, as the dome would be a shield against the elements, providing habitat for permaculture, aquaculture, whatever forms of horticulture.
Perhaps it's a Quaker-founded brewery, like Boswell's in Richmond, Indiana, with some of the ingredients right there in the dome with the tanks. Or the fermentation tanks could be in another facility, with caretakers living amidst the greenery.
So many permutations might be tried. So many experiments waiting to happen.
However, architects are not exploring these possibilities much in 2015.
Could we still build domes like the Climatron today? Perhaps in the Orient.
The Garden of Eden dome concept has become disconnected in the popular mind from Old Man River City (OMR). School children are not taught American history.